The pursuit of water security, fair distribution of water resources, and avoidance of conflicts related to their use and management are crucially linked to the development of a strong water governance framework. This framework is particularly relevant to the critical water situation in the Mediterranean region, highlighting the importance of effective water governance for the region�s sustainable and secure future. The water crisis in the Mediterranean illustrates the impact of good versus poor governance and the dynamics involved in striving for sustainable water resources at a regional level. Presently, the creation of a solid intra-regional water governance framework faces several obstacles, especially due to numerous independent regional initiatives. While there is no one-size-fits all solution for governance issues in the water sector, this brief emphasizes the importance of developing locally adapted, context-specific policies from multi-level governance perspectives.