The study is a part of the FES European Youth Studies project. It investigates the opinions of Czech youth on a broad range of topics, such as education, employment, political participation, family relationships, and values. Our findings reveal that pollution and climate change, social injustice and worries related to a global pandemic are the main worries of the Czech youth. Furthermore, they have very little interest in politics, do not want to take political functions, and are significantly less religious than their peers from the other Visegrad 4 countries. The study surveyed 1,500 respondents aged 15–29. In addition, qualitative fieldwork was conducted in the form of ten in-depth interviews and three focus-group interviews.