THOMAS POGGE| THE HEALTH IMPACT FUND would benefit most of all from the diffuse economic effects of a massive reduction in the global burden of disease. For the poor in less-developed countries the HIF would bring significant health gains, especially in regard to neglected diseases which are currently underfunded in pharmaceutical research. Politicians and potential funders should join forces in ini­tiating suitable pilots and in creating the Health Impact Fund as a global institution that brings justice to global health. 8